Pittsburgh Panthers versus Louisville Cardinals Friday Night College Football Betting Odds Free Pick

We came in with a winner on Thursday here as UAB gets the win and cover getting 10 points against an injury riddled Southern Mississippi team. Tonight we select from the Pittsburgh Panthers and Louisville Cardinals contest that airs at 8PM Eastern Time on ESPN. With our free pick we will play the Louisville Cardinals and Pittsburgh Panthers to go over 53.

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This is a tough spot for the Pittsburgh Panthers having to regroup after a blown game last week. The team last played on Saturday at NC State and then must travel back to Louisville for a Friday game. The defense will crack here for the Panthers in this tough back-to-back road spot in Louisville. Bet the over.

Bet Pittsburgh Panthers and Louisville Cardinals over 53

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